Repair of P Element-induced DNA Double-strand Breaks
DNA transposons are clearly delineated segments of DNA that have the ability to move about within a genome in a process known as transposition. Non-replicatioe, cutand-paste transposons are mobilized by the complete excision of the transposon from the genomic DNA, thus creating a DNA double-strand break at the transposon donor site. The P element transposon of Drosophila melanogaster transposes by a cut-and-paste mechanism, thereby providing a rich experimental system to study the repair of DNA double-strand breaks at a specific location in the genome.DNA transposons are clearly delineated segments of DNA that have the ability to move about within a genome in a process known as transposition.
| Title | : | Repair of P Element-induced DNA Double-strand Breaks |
| Author | : | Brian Tate Weinert |
| Publisher | : | - 2006 |
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