Stem Cell Engineering

Stem Cell Engineering

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While the potential of stem cells is recognized, their proliferation and differentiation must be more precisely controlled to maximize the production of therapeutically relevant cells and for cell replacement therapies to minimize contamination with residual cells that can give rise to side effects. How can engineers make contributions to address these challenges? With contributions from pioneers and experts, Stem Cell Engineering: Principles and Practices highlights recent advances in the understanding of the cellular and molecular composition of the stem cell niche, as well as approaches to build upon this basic information to direct stem cell differentiation into therapeutically valuable lineages. The growing recognition of stem cells as an important and exciting field will continue to draw investigators with diverse backgroundsa€”from biology, engineering, and the physical sciencesa€”and thereby enable further progress in these and other new directions. This book discusses advances made during the last decade that have led to increasingly defined culture systems for growing stem cells, starting from co-culture with feeder cells in the presence of serum to growth on synthetic substrates in defined medium. In addition to highlighting many recent advances, it underscores the need for future work.He graduated from Stanford University with a BS in chemical engineering in 1993 . ... Finally, he did a postdoctoral fellowship in the laboratory of Fred Gage at the Salk Institute for Biological Studies in La Jolla, California, before moving to UC Berkeley in 1999. ... Investigator Award, and the Whitaker Foundation Young Investigator Award, and he was named a Technology Review Top 100 Innovator.


Title:Stem Cell Engineering
Author: David Schaffer, Joseph D. Bronzino, Donald R. Peterson
Publisher:CRC Press - 2012-11-20
ISBN-13:

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